Preheat oven to 375 degrees F. Spray a 9×13-inch baking dish with non-stick spray. Set aside.
Boil lasagna noodles in a large pot of water according to package directions. Drain water. Carefully, lay out cooked lasagna noodles onto parchment paper to cool and dry.
In a medium bowl, stir together half the Alfredo sauce, all the shredded chicken, garlic powder, Italian seasoning, salt, pepper, and 1 cup of the mozzarella cheese. Mix to combine. Set aside.
Divide the chicken Alfredo mixture evenly among the 8 lasagna noodles, by spreading it evenly over each noodle. Roll up noodles starting at one end and roll up over the toppings. Place the roll-ups in the pan, one by one, seam-side down. Pour the remaining Alfredo sauce evenly over the top of each roll-up. Top evenly with remaining mozzarella cheese.
Bake uncovered for 20 minutes or until the cheese is melted and bubbly. Top with chopped parsley, if desired. Serve warm and enjoy!